tag:blogger.com,1999:blog-4082643038671225434.post244331571873708605..comments2023-10-07T01:34:01.774-07:00Comments on Case of the Day: SpidersCraighttp://www.blogger.com/profile/17072102331564743101noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-4082643038671225434.post-72494891250910794482008-03-21T10:22:00.000-07:002008-03-21T10:22:00.000-07:00SpidersThis is Marfan syndrome. The image shows ar...Spiders<BR/><BR/>This is Marfan syndrome. The image shows arachnodactyly with a positive thumb sign (a) such that the entire thumbnail protrudes beyond the ulnar border of the hand and a positive wrist sign (b) so that the thumb and fifth finger overlap when encircling the wrist. Along with the long arm span, scoliosis, and eye findings (ectopia lentis), this indicates Marfan’s. Marfan’s patients are likely to die from aortic root disease leading to aneurysmal dilatation, aortic regurgitation, and dissection.<BR/><BR/>Sources: UpToDate; nature.com (European Journal of Human Genetics; Marfan Syndrome: clinical diagnosis and management by John Dean).Craighttps://www.blogger.com/profile/17072102331564743101noreply@blogger.comtag:blogger.com,1999:blog-4082643038671225434.post-57399082687716881332008-03-19T22:23:00.000-07:002008-03-19T22:23:00.000-07:00thought it was ehler-danlos or marfan's. if marfa...thought it was ehler-danlos or marfan's. if marfan's, COD is possibly valve prolapseAlexhttps://www.blogger.com/profile/06972701448751949861noreply@blogger.com