tag:blogger.com,1999:blog-4082643038671225434.post2540882943274444376..comments2023-10-07T01:34:01.774-07:00Comments on Case of the Day: KodakCraighttp://www.blogger.com/profile/17072102331564743101noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-4082643038671225434.post-25530477337755964602009-03-27T08:47:00.000-07:002009-03-27T08:47:00.000-07:00Nice one!-KodakLeukocoria or white pupillary refle...Nice one!<BR/>-<BR/>Kodak<BR/><BR/>Leukocoria or white pupillary reflex can be caused by abnormalities in the lens (cataracts), vitreous (hemorrhage), or retina (retinoblastoma). This is retinoblastoma, which can also present with strabismus. About 25% of cases are bilateral and heritable, 15% are unilateral and inherited, and the rest are unilateral and sporadic. Often, there is an association with a genetic 13q deletion (13q14 encodes a nuclear tumor suppressor RB1 gene). If untreated, retinoblastoma will metastacize in 6 months and cause death in years.<BR/><BR/>Sources: UpToDate; Wikipedia.Craighttps://www.blogger.com/profile/17072102331564743101noreply@blogger.comtag:blogger.com,1999:blog-4082643038671225434.post-9867457790989309372009-03-25T09:27:00.000-07:002009-03-25T09:27:00.000-07:00Rb?Rb?Alexhttps://www.blogger.com/profile/06972701448751949861noreply@blogger.com