tag:blogger.com,1999:blog-4082643038671225434.post3643016698272633473..comments2023-10-07T01:34:01.774-07:00Comments on Case of the Day: TearsCraighttp://www.blogger.com/profile/17072102331564743101noreply@blogger.comBlogger5125tag:blogger.com,1999:blog-4082643038671225434.post-13670156854604532742009-12-21T16:00:08.738-08:002009-12-21T16:00:08.738-08:00exactly right! you guys are really good! am going ...exactly right! you guys are really good! am going to take a one week break - will be back next Monday.<br />-<br />Tears<br /><br />Red-orange secretions (urine, saliva, sweat, tears) are a side effect of rifampin, also hinted at with the "four drug therapy" (RIPE is isoniazid, rifampin, pyrazinamide, and ethambutol). Rifampin induces many cytochrome p450 enzymes and as a result can decrease the effectiveness of oral contraceptives.<br /><br />Source: UpToDate.Craighttps://www.blogger.com/profile/17072102331564743101noreply@blogger.comtag:blogger.com,1999:blog-4082643038671225434.post-53710526124234936602009-12-20T21:44:26.582-08:002009-12-20T21:44:26.582-08:00rifampin rev p450rifampin rev p450Alexhttps://www.blogger.com/profile/06972701448751949861noreply@blogger.comtag:blogger.com,1999:blog-4082643038671225434.post-32583557340701909252009-12-19T23:41:57.847-08:002009-12-19T23:41:57.847-08:00Recent treatment with rifampin?Recent treatment with rifampin?Eldennoreply@blogger.comtag:blogger.com,1999:blog-4082643038671225434.post-44348323838944755342009-12-19T10:07:04.494-08:002009-12-19T10:07:04.494-08:00Rifampicin induces CyP450.. which inturn metabolis...Rifampicin induces CyP450.. which inturn metabolises OCPs.. The four drugs she was getting was probably for TB and she should have been advised that OCPs would be ineffective at regular doses.. The red-orange tears occur due to the rifampicin.. In the third world countries this property of Rifampicin is used to monitor compliance of the patient with ATT..sidhttps://www.blogger.com/profile/11517529202444474417noreply@blogger.comtag:blogger.com,1999:blog-4082643038671225434.post-55239728056455892632009-12-18T10:50:20.362-08:002009-12-18T10:50:20.362-08:00because the "four" drugs she's takin...because the "four" drugs she's taking are TB med's.... rifampin to be exact. Holla!I. Kantnoreply@blogger.com