tag:blogger.com,1999:blog-4082643038671225434.post6151021467364385480..comments2023-10-07T01:34:01.774-07:00Comments on Case of the Day: CariniiCraighttp://www.blogger.com/profile/17072102331564743101noreply@blogger.comBlogger1125tag:blogger.com,1999:blog-4082643038671225434.post-50782658002292907212009-09-11T11:36:37.282-07:002009-09-11T11:36:37.282-07:00interesting thought, i like it, NMS presents with ...interesting thought, i like it, NMS presents with mental status change, hyperthermia, and ANS instability, but also muscle rigidity. I was actually getting at another diagnosis with the vertical nystagmus.<br />-<br />Carinii<br /><br />Carinii refers to the abbreviation PCP, pneumocystis jirovecii (previously carinii) pneumonia or phencyclidine, the molecule shown here. Phencyclidine is a cheap, easily manufactured synthetic hallucinogen that can be found as powder, tablet, crystal, and liquid, and can be ingested, inhaled, injected, or smoked. PCP binds NMDA receptors, dopamine, norepinephrine, and serotonin reuptake complexes, and opiate receptor complexes. The nystagmus is characteristic of PCP (but vertical nystagmus can also be seen in nicotine ingestion).<br /><br />Sources: UpToDate; Wikipedia.Craighttps://www.blogger.com/profile/17072102331564743101noreply@blogger.com