tag:blogger.com,1999:blog-4082643038671225434.post6239079770850483069..comments2023-10-07T01:34:01.774-07:00Comments on Case of the Day: The Acute AbdomenCraighttp://www.blogger.com/profile/17072102331564743101noreply@blogger.comBlogger1125tag:blogger.com,1999:blog-4082643038671225434.post-45625548042348909492008-10-06T06:33:00.000-07:002008-10-06T06:33:00.000-07:00The Acute AbdomenThis is acute intermittent porphy...The Acute Abdomen<BR/><BR/>This is acute intermittent porphyria (AIP), an autosomal dominant partial deficiency of porphobilinogen deaminase activity in heme synthesis. The clinical findings are diverse but often involve abdominal pain, GI complaints, abdominal distention, ileus, urinary symptoms, peripheral neuropathy, seizures, or psychiatric manifestations. Patients may be hypertensive between crises and have longstanding anxiety. Unlike other porphyrias, there are no cutaneous manifestations. Diagnosis is by detection of metabolites ALA and PBG in the urine.<BR/><BR/>Source: UpToDate.Craighttps://www.blogger.com/profile/17072102331564743101noreply@blogger.com