tag:blogger.com,1999:blog-4082643038671225434.post907864895248836121..comments2023-10-07T01:34:01.774-07:00Comments on Case of the Day: Pharmacology ICraighttp://www.blogger.com/profile/17072102331564743101noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-4082643038671225434.post-17455240842324530712012-05-07T13:32:15.088-07:002012-05-07T13:32:15.088-07:00it's dapto! Reflex hammer, you're right - ...it's dapto! Reflex hammer, you're right - it is neutralized by surfactant. In other types of infection, it is a reasonable drug for MRSA<br />-<br />Pharmacology I<br /><br />The drug shown is daptomycin. Daptomycin is inactived by pulmonary surfactant; thus, it is not useful in treatment of MRSA pneumonia.<br /><br />Sources: UpToDate; Wikipedia.Craighttps://www.blogger.com/profile/17072102331564743101noreply@blogger.comtag:blogger.com,1999:blog-4082643038671225434.post-40668110968676063252012-04-30T10:27:53.838-07:002012-04-30T10:27:53.838-07:00I had to look this one up: "Pulmonary surfact...I had to look this one up: "Pulmonary surfactant antagonizes daptomycin, and it should not be used to treat pneumonia."<br /><br />That was an awesome question!Reflex Hammerhttp://thereflexhammer.blogspot.comnoreply@blogger.com