I put together these medical challenges. The cases are hypothetical and do not necessarily represent actual or typical presentations of medical diseases. Disclaimer is at the bottom of this page.
Wednesday, April 30, 2008
Minoxidil
A 52 year old male presents with splenomegaly, fatigue, weakness, weight loss, pancytopenia, and a smear shown above.
Challenge: What is the diagnosis and what stain is shown in the image above?
This is hairy cell leukemia (minoxidil or Rogaine is used to promote hair regrowth). Hairy cell leukemia is a chronic B cell lymphoproliferative disorder; the cells have prominent irregular cytoplasmic projections. This is a stain for tartrate-resistant acid phosphatase (TRAP), characteristic of hairy cell leukemia.
A 52 year old male presents with splenomegaly, fatigue, weakness, weight loss, pancytopenia, and a smear shown above.
I think Rogaine is the last thing his B cells need :(
ReplyDeleteHairy cell leukemia, TRAP stain
it's a TRAP!
ReplyDeletehaha good job!
ReplyDelete-
Minoxidil
This is hairy cell leukemia (minoxidil or Rogaine is used to promote hair regrowth). Hairy cell leukemia is a chronic B cell lymphoproliferative disorder; the cells have prominent irregular cytoplasmic projections. This is a stain for tartrate-resistant acid phosphatase (TRAP), characteristic of hairy cell leukemia.
Sources: UpToDate; som.tulane.edu.