


Challenge: These outstanding clinical images are from NEJM, shown under Fair Use, in an article describing a 53 year old gentleman with hypercholesterolemia, hypertriglyceridemia, insulin resistance, and an infectious disease being treated by what class of drugs?
Now a Chronic Disease
ReplyDeleteThis patient has HIV and is being treated by protease inhibitors (specifically indinavir). A common class effect of protease inhibitors is lipodystrophy; the first image shows fat wasting of the face, the second image shows central obesity, and the third image shows a "buffalo hump."
Source: http://content.nejm.org/cgi/content/full/339/18/1296/F1