I put together these medical challenges. The cases are hypothetical and do not necessarily represent actual or typical presentations of medical diseases. Disclaimer is at the bottom of this page.
Friday, March 7, 2008
Star Light, Star...
A six year old girl begins to develop breast buds and menstrual periods. You note ovarian cysts as well as these findings.
Challenge: What's the diagnosis?
First image is in the public domain, second image shown under fair use.
McCune-Albright syndrome is a rare disorder with the triad of sexual precocity, café-au-lait pigmentation (first image), and polyostotic fibrous dysplasia of bone (second image). The molecular mechanism is a mutation in an alpha subunit of a G protein. It only occurs in girls.
Challenge: What's the diagnosis?
Madeline-Albright syndrome
ReplyDeleteStar Light, Star…
ReplyDeleteMcCune-Albright syndrome is a rare disorder with the triad of sexual precocity, café-au-lait pigmentation (first image), and polyostotic fibrous dysplasia of bone (second image). The molecular mechanism is a mutation in an alpha subunit of a G protein. It only occurs in girls.
Sources: UpToDate history.nih.gov; brighamrad.harvard.edu.