
This is a kidney biopsy from an African American patient with acute onset peripheral edema, low albumin, severe proteinuria, hypertension, and microscopic hematuria. The cause is idiopathic. On the biopsy, some other glomeruli look completely normal.
Challenge: What's the diagnosis?
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focal segmental
ReplyDeleteI had a patient with this today!
ReplyDeleteFocal segmental glomerulosclerosis
Neph
ReplyDeleteThis is focal segmental glomerulosclerosis (FSGS) which for unknown reasons is seen more commonly in African Americans. There are also inherited forms of FSGS and secondary causes of FSGS.
Sources: UpToDate; intramural.niddk.nih.gov.