You are the pathologist receiving this specimen from the operating room. This patient had encephalopathy, GI bleed, weight loss, and early satiety. Labs show thrombocytopenia, hypoalbuminemia, hyperbilirubinemia, and prolonged PT and PTT. AST, ALT, alkaline phosphatase, and gammaglutamyl transpeptidase are all elevated. A chart biopsy shows that these abnormalities have been going on for years.Challenge: What serum marker is often elevated in this disease?
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2 comments:
Alpha Feto Protein?
outstanding!
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Cut It Out
This is a hepatocellular carcinoma which develops in the setting of chronic liver disease such as viral hepatitis. Symptoms are usually due to underlying liver disease. AFP is often elevated.
Source: UpToDate, image originally from Richard Freeman.
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