This drawing from 1841 depicts an infant with contractures of multiple joints. This heterogeneous group of disorders is characterized by degeneration of motor neurons. Most cases are neurogenic (disorders of the CNS, genetic syndromes, and chromosomal aberrations), but a small fraction result from primary muscle disease. Severity is variable.
Challenge: What is this?
Image is in the public domain.
Thursday, October 17, 2013
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Curving of Joints
In Greek, curving of joints is arthrogryposis; the diagnosis is arthrogryposis multiplex congenita and the drawing is by Adolph Wilhelm Otto.
Sources: UpToDate; Wikipedia.
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