The following images are from patients undergoing chemotherapy, who have uncontrolled HIV, or who are taking high dose steroids. They all presented with seizures or focal neurologic signs.
This is a coronal T1-weighted MRI.
This CT was obtained in a patient who had a stroke.
Challenge: What's the diagnosis?
Images shown under Fair Use.
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Holy Water Sprinkler
An aspergillum is a liturgical instrument used to sprinkle holy water, and its shape resembles that of Aspergills under the microscope. The first image shows multiple ring-enhancing lesions with surrounding edema and mass effect. The second image shows abnormal soft tissue filling the ethmoidal air cell complex, nasal cavity, and maxillary sinus; the arrows show dural thickening and abnormal enhancement. The third image shows Aspergillus thrombosis and vascular invasion. These all show aspergillus CNS infection.
Source: UpToDate.
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