Monday, October 1, 2007


You are a fresh third year ready to begin your internal medicine clerkship at San Francisco General Hospital. As you get on the MUNI to get to SFGH, you see a guy sitting across from you with these lesions on his legs and nose:

When you and that man get off at the bus stop, he turns to you and says, "Ah, you must be a student doctor. What do you think I got?"

Challenge: What's the cause of the skin lesion? What else does this person have?

Related Questions:
1. What is the skin lesion called?

Image is in the public domain.

*This will be a two part case! The next part will be released on Wednesday.


emily hw said...

Kaposi's sarcoma- cancer of the lymphatic epithelium

associated with HIV and HHV-8 infection

Craig said...


The skin lesion is Kaposi's sarcoma, a tumor caused by human herpesvirus 8. The lesions are papular nodules or blotches, a tumor arising from lymphatic endothelial cells. The lesion is highly vascular and on histology, spindle cells are appreciated. In the 1980s, especially in San Francisco, an epidemic of Kaposi's sarcoma was related to HIV infection and AIDS.

Source: Wikipedia.