Friday, September 26, 2008


A Japanese patient presents with bilateral loss of vision and the red eye shown above. Fluid accumulating behind the retina leads to retinal elevation and predisposes him to a retinal detachment. You also notice the whitening of his eyelashes, white patches on the skin, a history of sterile meningitis, loss of hair, and an 8th nerve palsy. This disease is also seen in the Hispanic population.

Challenge: This is a hard one. What is it?

Image is in the public domain.


Alex said...


Craig Chen said...


This is Vogt-Koyanagi-Harada syndrome, the second leading cause of uveitis in Japan (after Behcet’s syndrome). It is presumably autoimmune.

Sources: UpToDate; Wikipedia.