Monday, April 27, 2009

Wolf

Alas, this week is pharmacology week.
An older Caucasian patient with a cardiac arrhythmia treated with the medication shown above presents with fever, myalgias, arthralgias, and pleuritis. Laboratory testing shows that the patient has antihistone antibodies and is ANA positive.

Challenge: What's the drug, and what's the disease?

Image is in the public domain.

3 comments:

tree said...

procainamide, drug-induced lupus erythematosus

Alex said...

procainamide?

Craig Chen said...

go chemistry!
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Wolf

Lupus means wolf in Latin. This is drug-induced lupus by procainamide. Other drugs that can cause lupus include hydralazine, minocycline, diltiazem, penicillamine, isoniazid, quinidine, anti-TNF, interferon-alfa, methyldopa, chlorpromazine, and practolol.

Sources: UpToDate; Wikipedia.