Friday, May 21, 2010


Challenge: If all these patients were also deaf, what would be your diagnosis?

All images are in the public domain.


Suheil said...

Congenital Syphillis

Craig Chen said...


This is congenital syphilis which can also present as stillbirth, neonatal death, and hydrops fetalis. Early manifestations within the first 5 weeks of life include cutaneous lesions, hepatosplenomegaly, jaundice, anemia, snuffles, metaphyseal dystrophy, and periostitis. Late manifestations are shown here: frontal bossing, short maxilla, high palatal arch, Hutchinson triad (blunted upper incisors shown in third image, interstitial keratitis shown in first image, and eighth nerve deafness), saddle nose shown in second image, and perioral fissures. The fourth image is "saber shins" or osteoperiostitis of the tibia. Syphilis is part of the TORCH congenital infections, hence the case title "burn."

Sources: UpToDate;