Thursday, September 23, 2010


This is a biopsy from a 50 year old woman who presented with tremor, sweating, heat intolerance, palpitations, anxiety, diarrhea, and inability to sleep. On exam, you note tachycardia, a wide pulse pressure, hypertension, a prominent stare and lid lag (but no proptosis). Surprised, you find a pelvic mass and ascites. There is no goiter and an iodine uptake test shows minimal uptake in the thyroid.

Challenge: What's going on?

Image shown under Fair Use.


sid said...

Dermoid cyst of ovary producing Thyroxine.. Struma Ovarii

tree said...

struma ovarii

Khaled Selim said...

Teratoma ?

Alex said...

struma ovarii

Craig Chen said...

really well done! i definitely did not remember struma ovarii / teratoma. i'm impressed :) see you in a week!


Struma ovarii is the presence of thyroid tissue in an ovarian tumor, almost always a teratoma. Note, the histology shows cartilage, adipose, intestinal glands, as well as thyroid tissue.

Sources: UpToDate;