Monday, October 24, 2011
This image is from a ward in 1918, filled with patients with the same disease. This disease typically presents with abrupt onset of fever, headache, muscle ache, malaise, cough, sore throat, and rhinorrhea. Exam shows hyperemic mucosa and mild cervical lymphadenopathy, but little else. Complications include persistent high fever, dyspnea, bilateral reticular or reticulonodular opacities, secondary infection, rhabdomyolysis, encephalitis, transverse myelitis, aseptic meningitis, and Guillain-Barre syndrome.
Challenge: What is the molecular mechanism by which such pandemics occur?
Image is in the public domain.