This is the biopsy of a supraclavicular lymph node in a patient with unexplained fever, weight loss, and night sweats. The serum LDH is up. You note these malignant B cells with prominent nuclei and basophilic cytoplasm. The nuclei are mostly round with vesicular chromatin and nucleoli apposed to the nuclear membrane.Challenge: What is it?
*Note: The next case is related to this one.
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Diffuse large B-cell lymphoma
Histo
This image shows a diffuse large B cell lymphoma (non-Hodgkin’s lymphoma). There are “B” symptoms present (fever, weight loss, night sweats).
Sources: UpToDate; www2.umdnj.edu.
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