As a hematologist, you are asked to see a 25 year old female with easy bruising and heavy periods. She says she's always been an easy bleeder with nosebleeds lasting 30 minutes and severe bleeding after wisdom tooth extraction. After she delivered her last child, she had heavy bleeding during the peripartum period and then 7 days after delivery. Her ob/gyn referred her to you. She denies any soft tissue or joint swelling. She denies using any NSAIDs or aspirin. Physical examination is normal. The pattern of inheritance is shown above. Her CBC including platelets is normal.
Challenge: What's the diagnosis?
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Wednesday, October 14, 2009
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4 comments:
Von Willebrand
von willebrand?
von Willebrand's disease
brilliant!
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Hematology Consult
This is von Willebrand disease, the most common inherited bleeding disorder, usually autosomal dominant.
Sources: UpToDate; Wikipedia.
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