Friday, March 27, 2009

Black Box

A 50 year old woman with a history of GERD and gastroparesis medicated with the drug shown above for the last few years presents to your practice. She has new onset involuntary repetitive movements of limbs, lip smacking, tongue protrusion, eye movements, blinking, puckering of lips, and impaired movement of hands.

Challenge: The FDA just issued a statement related to this. What's the diagnosis and what's the cause?

Image is in the public domain.


Alex said...

sounds like tardive dysknesia, metachlopramide?

Craig Chen said...

Wow! Nice job!

Black Box

The FDA recently issued a black box warning on metoclopramide (shown in the image) due to risk of tardive dyskinesia. This risk is higher in older women and patients receiving the drug for greater than 3 months.

Source: FDA; Wikipedia.