Challenge: This 2 year old has an increased risk of osteogenic sarcoma; what does he or she have?Image is in the public domain.
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I put together these medical challenges. The cases are hypothetical and do not necessarily represent actual or typical presentations of medical diseases. Disclaimer is at the bottom of this page.
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2 comments:
Rb?
Nice one!
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Kodak
Leukocoria or white pupillary reflex can be caused by abnormalities in the lens (cataracts), vitreous (hemorrhage), or retina (retinoblastoma). This is retinoblastoma, which can also present with strabismus. About 25% of cases are bilateral and heritable, 15% are unilateral and inherited, and the rest are unilateral and sporadic. Often, there is an association with a genetic 13q deletion (13q14 encodes a nuclear tumor suppressor RB1 gene). If untreated, retinoblastoma will metastacize in 6 months and cause death in years.
Sources: UpToDate; Wikipedia.
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