You do an away rotation in obstetrics in Turkey and saw several cases of the disease shown above, which is rarely seen in the United States. 60-75% of these newborns are deaf, 10-20% have cardiac malformations, and 10-25% have CNS defects.Challenge: What is it and why does it not exist in the United States?
Both images are in the public domain.
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Congenital Rubella Syndrome. MMR Vaccine in US.
yes, nicely identified.
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Elaine Benes
The title refers to a Seinfeld episode "The Muffin Tops" where Elaine Benes starts a business selling only muffin tops. This is congenital rubella syndrome, unfortunately resulting in neonatal cataracts (first image) and a blueberry muffin baby (second image). Rubella, or German measles, is a togavirus that usually causes a self-limited infection transmitted by direct droplet contact from nasopharyngeal secretions. The vaccine is a live, attenuated virus.
Sources: UpToDate; phil.cdc.gov.
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