Wednesday, October 14, 2009

Hematology Consult

As a hematologist, you are asked to see a 25 year old female with easy bruising and heavy periods. She says she's always been an easy bleeder with nosebleeds lasting 30 minutes and severe bleeding after wisdom tooth extraction. After she delivered her last child, she had heavy bleeding during the peripartum period and then 7 days after delivery. Her ob/gyn referred her to you. She denies any soft tissue or joint swelling. She denies using any NSAIDs or aspirin. Physical examination is normal. The pattern of inheritance is shown above. Her CBC including platelets is normal.

Challenge: What's the diagnosis?

Image is in the public domain.


tree said...

Von Willebrand

Alex said...

von willebrand?

Anonymous said...

von Willebrand's disease

Craig Chen said...

Hematology Consult

This is von Willebrand disease, the most common inherited bleeding disorder, usually autosomal dominant.

Sources: UpToDate; Wikipedia.