A 40 year old woman who complains of neck pain radiating to the jaw, sweating, palpitations, weight loss, and malaise. On exam, you palpate a diffuse tender mildly enlarged goiter. Review of systems is positive for a recent upper respiratory tract infection. She has a mild anemia and leukocytosis. ESR is markedly elevated. You schedule a nuclear exam for her, which is shown below.
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By the time the patient follows up after the test, she says her symptoms have changed completely. Now, she is feeling depressed, lethargic, cold, and constipated.
Challenge: What's your diagnosis?
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3 comments:
Subacute Thyroidits
de quervain's thyroiditis?
whoops! sorry about that, i got way behind, but yes you are correct!
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Nuclear
This is subacute thyroiditis (also called subacute granulomatous or nonsuppurative thyroitidtis, giant cell thyroiditis, De Quervains' thyroiditis). It is presumably caused by a viral infection or post-viral process. The Tc-99m pertechnetate scan shows poor uptake in the thyroid consistent with the diagnosis. There is a small focus of tracer uptake in the right upper pole representing an autonomous nodule as well.
Sources: UpToDate; med.harvard.edu.
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