A 56 year old African American male presents with severely pruritic skin rashes. For the last few years, he's had nonspecific scaling skin lesions and biopsies were unremarkable. A primary care doctor gave him the diagnosis of "nonspecific dermatitis." But now he comes to your dermatology clinic with scaly patches and plaques >5cm in diameter. They are confined to the trunk. He also has generalized erythroderma and lymphadenopathy.
A skin biopsy shows this:
The red arrow indicates a specific type of microabscess. The blue arrow shows mononuclear cells in the epidermis. A blood smear shows this:
Challenge: This is one of the weirder cancers you've seen. What is it?
Both images shown under fair use.