Monday, June 30, 2008

Histo (Part 1)

This is the biopsy of a supraclavicular lymph node in a patient with unexplained fever, weight loss, and night sweats. The serum LDH is up. You note these malignant B cells with prominent nuclei and basophilic cytoplasm. The nuclei are mostly round with vesicular chromatin and nucleoli apposed to the nuclear membrane.

Challenge: What is it?

*Note: The next case is related to this one.

Image shown under fair use.


tree said...

Diffuse large B-cell lymphoma

Craig said...


This image shows a diffuse large B cell lymphoma (non-Hodgkin’s lymphoma). There are “B” symptoms present (fever, weight loss, night sweats).

Sources: UpToDate;