Monday, December 22, 2014

Fad Diet

A 50 year old man with hyperlipidemia decides to make up a diet consisting entirely of the fruit shown above and juice from the fruit. He presents with aches and pains all over, and his CK is quite elevated. FYI, this is not a real diet.

Challenge: What fruit is shown above and what is the cause of the CK elevation?

Image shown under Creative Commons Attribution Share-Alike License, from Wikipedia.


RaH said...

This is a grapefruit, part of the citrus family.
Grapefruit is a great fruit, except when mixing it with medicine. it is an inhibitor for cytochromes.
grapefruit and grapefruit saft has been shown to increase the plasma concentration of drugs and mess with the metabolism of many moluecules.
this is probably the case here. it might have something to do with the high Potassium concentration found in this fruit
thats my guess, am i right?

Craig Chen said...

on the right track - nice job!
Fad Diet

Grapefruit inhibits CYP3A4 and this can lead to statin myopathy in conjunction with lovastatin, simvastatin, and atorvastatin.

Source: UpToDate.